Monoclonal Antibodies Shire Hardback Woodhead Publishing 9780081002964

Monoclonal AntibodiesMeeting the Challenges in Manufacturing, Formulation, Delivery and Stability of Final Drug Product\nAuthor(s): Steven Shire\nFormat: Hardback\nPublisher: Elsevier Science & Technology, United Kingdom\nImprint: Woodhead Publishing Ltd\nISBN-13: 9780081002964, 978-0081002964\nSynopsis\nMonoclonal antibodies (MAbs) are currently the major class of protein bio therapeutic being developed by biotechnology and pharmaceutical companies. Monoclonal Antibodies discusses the challenges and issues revolving around development of a monoclonal antibody produced by recombinant DNA technology into a therapeutic [url] book covers downstream processing which includes design of processes to manufacture the formulation, formulation design, fill and finish into closure systems and routes of administration. The characterization of the final drug product is covered where the use of biophysical methods combined with genetic engineering is used to understand the solution properties .