Chemistry and Molecular Aspects of Drug Design and Action - 9780367387365

CRC Press

Introduction: Rational Drug DesignBased Mainly on the Pathobiochemistry of the Disease. \nChemical, Biochemical, and Biological Aspects of Pathophysiological Conditions Inflammatory Mechanisms in Alzheimer\u2019s Disease and OtherNeurodegenerative Disorders.Treatment Development Strategies for Alzheimer\u2019s Disease.Lipoprotein-Associated Phospholipase A2 as a New PrognosticFactor for Coronary Artery Disease. New Molecular Targets for the Prevention and Treatment of Gastrointestinal Ulcers and Inflammation Stress Activates Corticotropin Releasing: Factor SignalingPathways: Implication in Functional Bowel Disorders. Classical Medicinal Chemistry Design, Synthesis, and Pharmacological Evaluation of High-Affinity and Selectivity Sigma-1 and Sigma-2 Receptor Ligands. Synthesis of Biologically Active Taxoids. From the Molecular Pharmacology to the Medicinal Chemistry of Cannabinoids. An Appraisal of Fomocaines: Current Situation and Outlook. Ligands for the GABA Recognition Site at the .