High-Throughput Lead Optimization in Drug Discovery
CRC Press
High-Throughput Lead Optimization in Drug DiscoveryAuthor(s): Tushar Kshirsagar\nFormat: Paperback\nPublisher: Taylor & Francis Ltd, United Kingdom\nImprint: CRC Press\nISBN-13: 9780367387716, 978-0367387716\nSynopsis\nA Single Source on Parallel Synthesis for Lead Optimization\n\nThe end of the previous millennium saw an explosion in the application of parallel synthesis techniques for making compounds for high-throughput screening. Over time, it became clear that more thought in the design phase of library development is necessary to generate high quality hits. More recently, the use of parallel synthesis techniques has shifted to applications beyond screening collections. Exploring the nuances of this technology, High-Throughput Lead Optimization in Drug Discovery describes the application of parallel synthesis to lead optimization and the design and synthesis of targeted libraries. \n\nExamine Case Studies that Cover a Range of Different Biological Targets \n\nFeaturing real-.
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