Pain by Chas Bountra, Rajesh Munglani, William K. Schmidt - 9780367446734

CRC Press

This book focuses on basic aspects, clinical aspects, and novel approaches to drug discovery. It deals with major advances in understanding the basic pathophysiology of pain and how it can be manipulated at the anatomical, physiological immunological, pharmaceutical, and psychological levels. > \nThis reference presents a detailed overview of approaches and techniques in the management of pain caused by tissue, nerve and central nervous system injuries, categorizing pain into a variety of syndromes and underlying mechanisms to aid the development of interventional pharmacologic measures. > Part 1: Basic Aspects 1. Mechanism-Based Classifications of Pain and Analgesic Drug Discovery 2. Sites of Analgesic Action 3. From Acute to Chronic Pain: Peripheral and Central Mechanisms 4. Central and Peripheral Components of Neuropathic Pain 5. A New Perspective on Signal Transduction in Neuropathic Pain: The Emerging Role of the G Protein \u03B2\u03B3 Dimer in Transducing and Modulating OK