Drug-Drug Interactions - 2nd Edition

Name: Drug-Drug Interactions - 2nd Edition
Brand: CRC Press

CRC Press

Drug-Drug InteractionsAuthor(s): A. David Rodrigues\nFormat: Paperback\nPublisher: Taylor & Francis Ltd, United Kingdom\nImprint: CRC Press\nISBN-13: 9780367452742, 978-0367452742\nSynopsis\nAuthored by renowned leaders in the field, this comprehensive volume covers all aspects of drug-drug interactions, including preclinical, clinical, toxicological, and regulatory perspectives.\n\nThoroughly updated, this second edition reflects the significant advances and includes extensive new material on:\n\nkey interplay between transporters and enzymes in drug metabolism and drug interactions\nthe integral role of pharmacogenetics in metabolism-based drug-drug interactions\nin vivo in vitro correlations (reversible, mechanism-based inhibition, induction)\nin silico approaches enabling structure-activity and structure-function studies\nhigh-throughput screening and GLP methods for evaluating drug interactions in vitro\nthe use of transgenic animal models to evaluate drug interactions\n\nP.