Protein Phosphorylation in Aging and Age-Relate, Mattson,#

Protein Phosphorylation in Aging and Age-Related DiseaseAuthor(s): Paul Mark Mattson\nFormat: Hardback\nPublisher: Elsevier Science & Technology, United Kingdom\nImprint: Elsevier Science Ltd\nISBN-13: 9780444515834, 978-0444515834\nSynopsis\nIt can be argued that ATP is the most important molecule in cells. Not only is ATP the key energy source for cells, but it is also the source of phosphate groups that are transferred to a variety of substrate proteins via the action of elaborate families of protein kinases. An equally elaborate array of protein phosphatases can remove phosphate groups from proteins. It is now well established that protein phosphorylation is a widely used mechanism for cells to selectively modulate the function of a variety of proteins including enzymes, ion channels and pumps and structural proteins. In this volume of ACAG leading experts describe the evidence that protein phosphorylation is altered in aging and age-related disease. Protein phosphorylation .