Evaluation of Drug Candidates for Preclinical Development by ... - 9780470044919

Evaluation of Drug Candidates for Preclinical DevelopmentPharmacokinetics, Metabolism, Pharmaceutics, and Toxicology\nAuthor(s): Chao Han, Charles B. Davis, Binghe Wang\nFormat: Hardback\nPublisher: John Wiley & Sons Inc, United States\nImprint: John Wiley & Sons Inc\nISBN-13: 9780470044919, 978-0470044919\nSynopsis\nEmphasizes the integration of major areas of drug discovery and their importance in candidate evaluation\n\n It is believed that selecting the \""right\"" drug candidate for development is the key to success. In the last decade, pharmaceutical R departments have integrated pharmacokinetics and drug metabolism, pharmaceutics, and toxicology into early drug discovery to improve the assessment of potential drug compounds. Now, Evaluation of Drug Candidates for Preclinical Development provides a complete view and understanding of why absorption-distribution-metabolism-excretion-toxicology (ADMET) plays a pivotal role in drug discovery and development.\n\n Encompassing .