Essentials of Pharmaceutical Preformulation, Gaisford, Saunders 97804709 PB^+

Essentials of Pharmaceutical PreformulationAuthor(s): Simon Gaisford, Mark Saunders\nFormat: Paperback\nPublisher: John Wiley and Sons Ltd, United Kingdom\nImprint: Wiley-Blackwell\nISBN-13: 9780470976364, 978-0470976364\nSynopsis\nEssentials of Pharmaceutical Preformulation is a study guide which describes the basic principles of pharmaceutical physicochemical characterisation. Successful preformulation requires knowledge of fundamental molecular concepts (solubility, ionisation, partitioning, hygroscopicity and stability) and macroscopic properties (physical form, such as the crystalline and amorphous states, hydrates, solvates and co-crystals and powder properties), familiarity with the techniques used to measure them and appreciation of their effect on product performance, recognising that often there is a position of compromise to be reached between product stability and bioavailability.\n\n This text introduces the basic concepts and discusses their wider implication for pharmag