Structure-Function Analysis of G Protein-Coupled Receptors by... - 9780471252283

Structure-Function Analysis of G Protein-Coupled ReceptorsAuthor(s): Jrgen Wess\nFormat: Hardback\nPublisher: John Wiley & Sons Inc, United States\nImprint: Wiley-Liss Inc.,U.S.\nISBN-13: 9780471252283, 978-0471252283\nSynopsis\nG protein-coupled receptors (GPCRs) are the largest single class of receptors in biology, often playing key roles in a remarkably large number of physiological and pathophysiological conditions. GPCRs or GPCR-dependent signalling pathways are the targets of a very large number of therapeutically useful drugs. Detailed knowledge about the molecular structure of GPCRs should therefore pave the way for the design of novel drugs with increased efficacy and specificity.\n This volume provides a concise, up-to-date presentation of methods (including molecular genetic, biochemical, and biophysical) which have been used successfully in studying the structure and function of GPCRs. With contributions from international leaders in the field, the editor provides ovee