Drug Discovery with Privileged Building Blocks by Jie Jack Li... - 9781032041735

CRC Press

Drug Discovery with Privileged Building BlocksTactics in Medicinal Chemistry\nAuthor(s): Jie Jack Li, Minmin Yang\nFormat: Hardback\nPublisher: Taylor & Francis Ltd, United Kingdom\nImprint: CRC Press\nISBN-13: 9781032041735, 978-1032041735\nSynopsis\nDrug Discovery with Privileged Building Blocks traces back PharmaBlocks founding philosophy of designing privileged building blocks. High-quality building blocks are crucial not only to biological activities of different molecules but also to ADMET properties, which eventually will impact the success rate of drug discovery projects. A thorough study of how building blocks perform in drug molecules and a regular analysis of new building block structures in the latest researches have proven to be a fruitful strategy to generate novel building blocks. Using this strategy, PharmaBlock has supplied the drug industry with a great number of building blocks, which are increasingly being adopted by drug hunters, and these are identified in t.