CRC Handbook of Eicosanoids, Volume II

CRC Press

Building upon the extensive compilation of biochemical data featured in Volume I of the Handbook of Eicosanoids, Volume II describes the past, present, and potential future impact of eicosanoid research on new drug development. > Building upon the extensive compilation of biochemical data featured in Volume I of the Handbook of Eicosanoids, the new Volume II describes the past, present, and potential future impact of eicosanoid research on new drug development. The reader is taken from a historical perspective through state-of-the-art basic concepts to extensive tabulation of molecular structures of compounds known to act via the eicosanoid system. Much emphasis is given to recent breakthroughs in the mechanism of action of anti-inflammatory corticosteroids and the development of receptor antagonists for prostaglandins and leukotrienes. There is also an introductory chapter that proposes areas that require further investigation and novel approaches using existing technology. This .