Design and Analysis of Clinical Trials with Time-to-Event Endpoints

Name: Design and Analysis of Clinical Trials with Time-to-Event Endpoints
Brand: CRC Press

CRC Press

Design and Analysis of Clinical Trials with Time-to-Event EndpointsAuthor(s): Karl E. Peace\nFormat: Hardback\nPublisher: Taylor & Francis Ltd, United Kingdom\nImprint: Chapman & Hall/CRC\nISBN-13: 9781420066395, 978-1420066395\nSynopsis\nUsing time-to-event analysis methodology requires careful definition of the event, censored observation, provision of adequate follow-up, number of events, and independence or \""noninformativeness\"" of the censoring mechanisms relative to the event. Design and Analysis of Clinical Trials with Time-to-Event Endpoints provides a thorough presentation of the design, monitoring, analysis, and interpretation of clinical trials in which time-to-event is of critical interest.\n\nAfter reviewing time-to-event endpoint methodology, clinical trial issues, and the design and monitoring of clinical trials, the book focuses on inferential analysis methods, including parametric, semiparametric, categorical, and Bayesian methods; an alternative to the Cox .