Anticancer Agents from Natural Products - 2nd Edition
CRC Press
The approach to drug discovery from natural sources has yielded many important new pharmaceuticals inaccessible by other routes. In many cases the isolated natural product may not be an effective drug for any of several reasons, but it nevertheless may become a drug through chemical modification or have a novel pharmacophore for future drug design. In summarizing the status of natural products as cancer chemotherapeutics, Anticancer Agents from Natural Products, Second Edition covers the:\n\n--History of each covered drug\u2014a discussion of its mechanism on action, medicinal chemistry, synthesis, and clinical applications \n--Potential for novel drug discovery through the use of genome mining as well as future developments in anticancer drug discovery \n--Important biosynthetic approaches to \""unnatural\"" natural products\nAnticancer Agents from Natural Products, Second Edition discusses how complex target-oriented synthesis\u2014enabled by historic advances in methodology\u2014has.
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