Skeletal Development and Remodeling in Health, Disease and Aging Zaidi Paperback

Skeletal Development and Remodeling in Health, Disease and Aging, Volume 1068Author(s): Mone Zaidi\nFormat: Paperback\nPublisher: John Wiley and Sons Ltd, United Kingdom\nImprint: Wiley-Blackwell\nISBN-13: 9781573315838, 978-1573315838\nSynopsis\nOur understanding of how the skeleton is remodeled and repaired has been enormously expanded in the past decade. \nUsing advanced molecular technologies including transgenesis, gene knockout, and gene array, we are gaining a better understanding of both the precise pathways through which osteoblasts lay down new bone and how osteoclasts remove old bone. These studies have not only helped us understand the basic biological properties of the skeleton and how it responds to hormonal, cytokine, and mechanical stimulation, but also, in some instances, clarified the source of pathophysiology.\n\n The eventual goal of such discoveries is to lay down a firm scientific foundation for the identification of novel cellular and molecular targets for futu.