Genetics of Common Diseases: Future Therapeutic and Diagnostic Possibilities (U

CRC Press

Many common diseases are partly attributable to the genes which an individual inherits > Many common diseases are partly attributable to the genes which an individual inherits. Early steps have now been made in developing ways to determine which genetic variations are important, with some recent successes. In parallel, ways to improve healt > Contributors -- Abbreviations -- Preface -- 1 Perspectives in human linkage studies. /S. Povey -- Pairwise linkage analysis of Mendelian traits -- Finding the cause of a disease which shows clear Mendelian inheritance -- After a LOO score of +3, what next? -- Narrowing the search by searching for critical recombinants -- Linkage disequilibrium -- Linkage analysis in more complex situations -- Linkage in complex traits -- Why are we doing this? -- References -- 2 Twin research: nature versus nurture in common diseases. /K.O. Kyvik -- Introduction -- History -- Biology of twinning -- Demography -- Twin studies -- Assumptions -- T he concep.