Acute Promyelocytic Leukemia: A Clinical Guide by Oussama Abla

Acute Promyelocytic LeukemiaA Clinical Guide\nAuthor(s): Oussama Abla, Francesco Lo Coco, Miguel A. Sanz\nFormat: Paperback\nPublisher: Springer Nature Switzerland AG, Switzerland\nImprint: Springer Nature Switzerland AG\nISBN-13: 9783030097134, 978-3030097134\nSynopsis\nThis book provides a comprehensive overview on the clinical issues and biology of acute promyelocytic leukemia (APL) and on the molecular mechanisms of targeted therapy with ATRA and ATO. The text covers major topics such as the pathophysiology of APL coagulopathy, biologic and clinical differences between children and adults with APL, and the role of minimal residual disease monitoring. Additionally, the book summarizes historical, current, and future treatment strategies in both adults and children, while highlighting the most recent therapeutic recommendations for relapsed disease and the evolving indications for autologous and allogeneic stem cell transplant. This volume also features chapters focusing on seconda.